Absorption, Bioavailability, and Metabolism of Flavonoids
نویسندگان
چکیده
منابع مشابه
Food content, processing, absorption and metabolism of onion flavonoids.
The question as to how far the development of chronic diseases in humans depends on diet still remains open. Simultaneously, epidemiological studies suggest the consumption of a flavonoids rich diet might decrease the risk of degenerative changes and certain diseases. The intake of this group of compounds as to quality and quantity depends on dietary habits and a widespread presence of querceti...
متن کاملIntestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats.
Herba Epimdii is a traditional Chinese medicine used to treat osteoporosis. Its main pharmacological ingredients are flavonoids. In previous studies conducted in healthy animals, we showed that epimedium flavonoids could be hydrolyzed into secondary glycosides or aglycon by intestinal flora or enzymes, thereby enhancing their absorption and antiosteoporosis activity. To study the medicine in th...
متن کاملBioavailability of Dietary Carotenoids: Intestinal Absorption and Metabolism
Various carotenoids with diverse structures are present in foods and have been reported to have beneficial effects on human health. Owing to their hydrophobicity, however, poor solubilization in the aqueous milieu of the digestive tract restricts their intestinal absorption. Fats and oils were found to increase the solubilization of carotenoids into mixed-micelles, which would therefore enhance...
متن کاملOral Absorption, Intestinal Metabolism and Human Oral Bioavailability
Most of the drugs that are available in the marketplace are administered via the oral route, which is a convenient and cost effective route of administration (Lipinski 1995; Lipinski 2000; Lipinski et al. 2001; Lipinski 2004; Abrahamsson and Lennernas 2005). Thus, oral bioavailability is one of the key considerations for discovery and development of a new chemical entity (NCE). It is well recog...
متن کاملBerry flavonoids and phenolics: bioavailability and evidence of protective effects.
Berries contain vitamin C and are also a rich source of phytochemicals, especially anthocyanins which occur along with other classes of phenolic compounds, including ellagitannins, flavan-3-ols, procyanidins, flavonols and hydroxybenzoate derivatives. This review examines studies with both human subjects and animals on the absorption of these compounds, and their glucuronide, sulphate and methy...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2004
ISSN: 1388-0209,1744-5116
DOI: 10.3109/13880200490893492